Michael W DeGregorio Selected Research

Ospemifene

1/2017	Repurposing ospemifene for potentiating an antigen-specific immune response.
11/2014	Ospemifene: a first-in-class, non-hormonal selective estrogen receptor modulator approved for the treatment of dyspareunia associated with vulvar and vaginal atrophy.
1/2014	Safety and efficacy of ospemifene for the treatment of dyspareunia associated with vulvar and vaginal atrophy due to menopause.
3/2013	Ospemifene, vulvovaginal atrophy, and breast cancer.
1/2012	Ospemifene and 4-hydroxyospemifene effectively prevent and treat breast cancer in the MTag.Tg transgenic mouse model.
6/2008	Pharmacologic effects of ospemifene in rhesus macaques: a pilot study.
1/2006	Ineffectiveness of American ginseng in the prevention of dimethylbenzanthracene-induced mammary tumors in mice.
3/2005	Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women.
1/2005	Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ.
1/2003	Pharmacokinetics of selective estrogen receptor modulators.

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Michael W DeGregorio Research Topics

Disease

11	Neoplasms (Cancer) 01/2017 - 01/2005
6	Atrophy 11/2014 - 03/2005
6	Breast Neoplasms (Breast Cancer) 11/2014 - 07/2002
4	Lung Neoplasms (Lung Cancer) 07/2015 - 03/2013
3	Dyspareunia 01/2017 - 01/2014
3	Carcinoma (Carcinomatosis) 10/2013 - 01/2005
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2014 - 03/2013
2	Carcinogenesis 03/2013 - 01/2005
2	Osteoporosis 01/2003 - 07/2002
1	Melanoma (Melanoma, Malignant) 01/2016
1	Atrophic Vaginitis 11/2014
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2013
1	Transitional Cell Carcinoma 10/2013
1	Urinary Bladder Neoplasms (Bladder Cancer) 10/2013
1	Inflammation (Inflammations) 03/2013
1	Thromboembolism 01/2012
1	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2005
1	Hot Flashes 01/2003
1	Vaginal Discharge 01/2003
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2002

Drug/Important Bio-Agent (IBA)

11	OspemifeneIBA 01/2017 - 07/2002
5	CytokinesIBA 01/2017 - 03/2013
5	Tamoxifen FDA LinkGeneric 11/2014 - 07/2002
5	Selective Estrogen Receptor Modulators (SERM)IBA 11/2014 - 07/2002
4	AntigensIBA 01/2017 - 03/2013
4	Estrogens (Estrogen)FDA Link 11/2014 - 01/2012
3	Estrogen ReceptorsIBA 01/2017 - 01/2012
3	Cisplatin (Platino)FDA LinkGeneric 07/2015 - 06/2014
3	L-BLP25IBA 06/2014 - 03/2013
3	Toremifene (Fareston)FDA Link 01/2014 - 07/2002
2	Mucin-1 (CA 15-3 Antigen)IBA 06/2014 - 10/2013
2	CarcinogensIBA 10/2013 - 03/2013
2	LY 353381 (LY353381)IBA 01/2003 - 07/2002
2	Raloxifene Hydrochloride (Evista)FDA Link 01/2003 - 07/2002
1	Cancer VaccinesIBA 01/2017
1	Peptides (Polypeptides)IBA 01/2017
1	VaccinesIBA 01/2016
1	AntibodiesIBA 01/2016
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2016
1	Monoclonal AntibodiesIBA 01/2016
1	MicroRNAs (MicroRNA)IBA 07/2015
1	LigandsIBA 07/2015
1	PlatinumIBA 04/2015
1	DNA AdductsIBA 04/2015
1	ImmunosorbentsIBA 06/2014
1	EnzymesIBA 06/2014
1	Interferon-gamma (Interferon, gamma)IBA 10/2013
1	Protein Subunit VaccinesIBA 10/2013
1	hydroxide ionIBA 10/2013
1	ButylhydroxybutylnitrosamineIBA 10/2013
1	Interleukin-4 (Interleukin 4)IBA 10/2013
1	Urethane (Ethyl Carbamate)IBA 03/2013
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2013
1	Pharmaceutical PreparationsIBA 01/2012
1	4-hydroxyospemifeneIBA 01/2012
1	Anticarcinogenic AgentsIBA 01/2006
1	LasofoxifeneIBA 07/2002
1	idoxifeneIBA 07/2002
1	droloxifeneIBA 07/2002
1	LipidsIBA 07/2002

Therapy/Procedure

5	Immunotherapy 01/2016 - 03/2013
5	Drug Therapy (Chemotherapy) 01/2016 - 03/2013
5	Therapeutics 06/2014 - 01/2003
2	Chemoradiotherapy 07/2015 - 01/2014
2	Radiotherapy 07/2015 - 06/2014
1	Microspheres (Microsphere) 10/2013
1	Intraperitoneal Injections 03/2013
1	Chemoprevention 01/2005
1	Transplantation 01/2005